What are some good reasons to not use a filter?

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One good reason to not use a filter when working with 10ul Filter Tips is when the solution being filtered contains particles or debris that are larger than the filter pore size, which may result in clogging and potential loss of sample. Another reason may be that the filter material may interfere with downstream applications, such as PCR or protein assays. In such cases, it may be more appropriate to use a different type of purification method or a larger pore size filter.

MBP INC Asked question March 14, 2023